Certain shares of IGM Biosciences, Inc. common stock are subject to a lock-up agreement ending 29-MAY-2022.

Certain shares of IGM Biosciences, Inc. common stock are subject to a lock-up agreement ending 29-MAY-2022. These ordinary shares will be blocked for 60 days from 30-MAR-2022 to 29-MAY-2022. Details: The Directors and Officers (the “Locking Parties”) and the Company have agreed that, without the prior written consent of the Representatives on behalf of the Underwriters, the Company and they will not, and will not cause it to publicly disclose its intention, during the period ending 60 days after the date of this Prospectus Supplement (the “Restricted Period”), to sell, offer to sell, enter into an agreement to sell or lend Common Shares or options, warrants or rights to acquire common stock or securities exchangeable or exercisable or convertible into common stock, or to acquire other securities or rights ultimately exchangeable, exercisable or convertible into common stock (“Securities ”), effect a short sale, or establish or increase an “equivalent selling position” (as defined in Rule 16a-1(h) under the Exchange Act) or liquidate or reduce any “po Equivalent Appeal Position” (as defined in Rule 16a-1(b) under the Exchange Act) of any common stock or related securities, to pledge, hypothecate or grant a security interest in any common stock or related securities , otherwise transfer or assign common stock of stock or related securities, enter into any swap, hedge or similar arrangement or agreement that transfers, in whole or in part, the economic risk of stock ownership shares or related securities, whether or not such transaction is to be settled in securities, cash or otherwise, announce the offering of common shares or related securities, submit or file a registration statement under the securities with respect to any common stock or related securities (other than the common stock offered hereby), effect a stock consolidation, recapitalization, stock consolidation, reclassification or nsimilar action affecting outstanding common stock or publicly announcing any intention to do any of the foregoing actions.

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